In a future where Earth was partially destroyed by an invasion of interdimensional creatures known as Behemoths, the surviving humanity built mega-cities protected by energy walls.
To confront these threats, a militarized law enforcement organization called F.R.A.G. (Force Recon Against Giants) was founded, a fighting force equipped with biochemical weapons, enhanced armor, and special implants that grant each agent a Mastery Technique, based on an energy source called the "Anima Core."