The Raptors followed closely behind the Cavaliers with 56 wins, ranking third, with DeRozan and Lowry both delivering the best seasons of their careers.
The Celtics secured the fourth spot with 50 wins, surging into the top half of The East with a string of consecutive victories.
Following them, the Hawks and the Hornets both ended up with 48 wins, ranking fifth and sixth respectively.
The Pacers claimed the seventh spot with 47 wins and would face off against the Cavaliers in the first round.
The final spot in The East went to the Pistons with 44 wins, after they emerged victorious in a crucial game against the Bulls.
The Bulls, on the other hand, had their worst season in recent years, ending with just 42 wins, a record that would have been enough to secure a playoff spot in The West.