"The theory is feasible, but we need to know the epitopes exposed by PAC-FUS1 on the cell surface." Song Zimo said, "Fusion proteins often generate new antigen epitopes, which may be ideal targets."
"We have preliminary mass spectrometry data." Catherine pulled up another document, "The extracellular part of PAC-FUS1 mainly originates from the original adhesion molecule, but a new short peptide sequence near the fusion point has been generated, approximately 15 amino acids, which has never been expressed in normal human tissues and should be a tumor-specific new antigen."
Yang Ping carefully examined the sequence: "If this sequence is indeed exposed on the cell surface and its conformation is stable, it would be an excellent target. However, we need to verify its accessibility, and I think it might serve as our supplement. By researching their differences, I can uncover more secrets."
